Doxazosin prescribed for BPH acts mainly by which mechanism?</n>

Doxazosin prescribed for BPH acts mainly by which mechanism?</n>

• A. Relaxing smooth muscle in the bladder neck and prostatic urethra
• B. Killing bacteria in the urinary tract
• C. Increasing diuresis to reduce urine volume
• D. Decreasing testosterone production

Answer: (A)

Doxazosin is an alpha-1 adrenoceptor blocker used for BPH. Its main action is to relax smooth muscle in the bladder neck and prostatic urethra. By easing the tightness in these areas, urine can flow more freely, reducing obstruction and improving voiding symptoms. Killing bacteria would be the role of an antibiotic, not doxazosin. Increasing urine production comes from diuretics, which alter fluid balance rather than urinary tract smooth muscle. Decreasing testosterone production would involve agents like 5-alpha-reductase inhibitors, which shrink the prostate over time, but that’s a different mechanism from alpha-1 blockade.

Doxazosin is an alpha-1 adrenoceptor blocker used for BPH. Its main action is to relax smooth muscle in the bladder neck and prostatic urethra. By easing the tightness in these areas, urine can flow more freely, reducing obstruction and improving voiding symptoms.

Killing bacteria would be the role of an antibiotic, not doxazosin. Increasing urine production comes from diuretics, which alter fluid balance rather than urinary tract smooth muscle. Decreasing testosterone production would involve agents like 5-alpha-reductase inhibitors, which shrink the prostate over time, but that’s a different mechanism from alpha-1 blockade.